Hepatitis being first manifestation of secondary syphilis is rare.Here in we report Preamps a case of 39 years old male who was being treated for hepatitis and presented to us subsequently with itchy maculopapular rash.Venereal disease research laboratory INDOLE-3-CARBINOL (VDRL) titre was 1:16.Treponema pallidum hemagglutination assay (TPHA) was positive.He was treated with intramuscular Benzathine Penicillin.
His hepatitis improved rapidly.